This stuff has all been done on bacteria long ago, but these guys did this study in human cells. What genes (proteins!) are 100% essential for human cells to survive? Probably worth clarifying this statement -- what genes are 100% essential for human cells to survive in culture...cause thats the only way you're gonna pull this one off.
They come up with a list of 2,000. Wow, right? Depending on how you look at that, its either really big...or surprisingly small. I can't decide.
Are we surprised at all that a ton of them are proteins involved in protein glycosylation? Apparently that stuff is important.
Link here!
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