I don't have a ton of MALDI experience. A little here and there, but I've always found it fascinating. I ran one a few times in grad school and I was very turned off by having to calibrate it constantly throughout the day. That might have been the start of my TOF hatred, come to think of it...
What I want is MALDI on a modern Orbitrap, like the Fusion above. Thats the MassTech APMALDI-HR. Some friends of mine got to mess around with one and what I hear is that it is excellent!
You can check it out here!
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