Cool tips in this month's Mascot Newsletter for those of you who are studying weird things that haven't gotten fully annotated genomes. Search with your MS/MS data against Expressed Sequence Tags (EST). The newsletter highlights one fish that only has 1,200 annotated proteins but nearly a quarter-million ESTs. Sure, its more work for you to sort it out, but it beats only coming up with 1,200 proteins and they'll annotate it all someday!
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